Uptake of Nicotinic Acid-C14 and Nicotinamide-C14 by Ascites Cells in Vitro

Nicotinic acid and nicotinamide metabolism in ascites cells in vitro.

The studies reported here are primarily concerned with the metabolism of vitamin-containing nucleotides in intact cells. Holzer, Friedrich, and Grisebach (I) have reported that the Ehrlich ascites cells incorporated nicotinic acid-C4 slowly into nicotinamide adenine dinucleotide. Since, under the same conditions, nicotinamide-Cl4 was rapidly incorporated into nicotinamide adenine dinucleotide, ...

Metabolism of pyruvic acid-2-C14 and hydroxypyruvic acid-2-C14 in algae.

The metabolism of pyruvic acid in the light and dark by Scenedesmus has been examined with two aims: to study the relationship of its metabolism to that of the intermediates of C1402 fixation and to compare its metabolic fate with that of hydroxypyruvate. The metabolism of hydroxypyruvic acid was compared with that of C1402 fixation in order to ascertain whether it might be a photosynthetic int...

The metabolism of ascorbic acid-1-C14 and oxalic acid-C14 in the rat.

It is known that oxalic acid is a product of ascorbic acid metabolism in the guinea pig (1) and rat (2), and is formed in man from unidentified precursors (3). Oxalates are also of interest because of their occasional toxicity and unexplained deposition. Ascorbic, dehydroascorbic, and 2,3diketogulonic acids are known to give rise to oxalic and threonic acids in approximately quantitative yields...

Metabolism of Coprostanol-c14 and Cholestanol-4-c14 in Man.

Uptake of Adenine-8-C14 and Orotic-6-C14 Acid into Nuclear DNA of Non-Dividing Cells in the Adult Feline Neuraxis

A biochemical investigation (1, 2) of the incorporation of adenine-8-C '4 and orotic-6-C 14 acid into the nucleic acids of the adult feline neuraxis showed rapid uptake of these precursors into pentosenucleic acid (PNA) in both white and gray matter. Deoxypentosenucleic acid (DNA) exhibited little, if any, uptake in short term experiments. In chronic experiments, however, the D N A fraction acq...